Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

MicroRNA-Mediated Suppression of Glial Cell Line-Derived Neurotrophic Factor Expression Is Modulated by a Schizophrenia-Associated Non-Coding Polymorphism.

International journal of molecular sciences - 19 Apr 2024

Keszler Gergely, Vékony Bálint, Elek Zsuzsanna, Nemoda Zsófia, Angyal Nóra, Bánlaki Zsófia, Kovács-Nagy Réka, Rónai Zsolt, Réthelyi János M

Abstract excerpt

Plasma levels of glial cell line-derived neurotrophic factor (GDNF), a pivotal regulator of differentiation and survival of dopaminergic neurons, are reportedly decreased in schizophrenia. To explore the involvement of GDNF in the pathogenesis of the disease, a case-control association analysis was performed between five non-coding single nucleotide polymorphisms (SNP) across the GDNF gene and schizophrenia. Of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to 3' Untranslated Regions
Share to Binding Sites

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Case-Control Studies

Share to Gene Expression Regulation

Share to Glial Cell Line-Derived Neurotrophic Factor

Share to HEK293 Cells

Share to MicroRNAs

Share to Schizophrenia

Source

Open in PubMed Open full text

Identifiers

PMID: 38674063
DOI: 10.3390/ijms25084477
PMCID: PMC11050407

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

MicroRNA-Mediated Suppression of Glial Cell Line-Derived Neurotrophic Factor Expression Is Modulated by a Schizophrenia-Associated Non-Coding Polymorphism.PMID 38674063Read ↗

Association analysis of the glial cell line-derived neurotrophic factor (GDNF) gene in schizophrenia.Semantic proximity Read ↗

Glial cell line-derived neurotrophic factor (GDNF) gene and schizophrenia: polymorphism screening and association analysis.Semantic proximity Read ↗

A MicroRNA gene is hosted in an intron of a schizophrenia-susceptibility gene.Semantic proximity Read ↗

Alterations in the Expression Levels of miR-9-5p and miR-4467 in Peripheral Blood of Patients with First-Episode SchizophreniaSemantic proximity Read ↗

Schizophrenia-Associated MIR204 Regulates Noncoding RNAs and Affects Neurotransmitter and Ion Channel Gene Sets.Semantic proximity Read ↗

Glial cell line-derived neurotrophic factor receptor alpha 2 (GFRA2) gene is associated with tardive dyskinesia.Semantic proximity Read ↗

Schizophrenia-associated rs4702 G allele-specific downregulation of FURIN expression by miR-338-3p reduces BDNF production.Semantic proximity Read ↗

Brain derived neurotrophic factor (BDNF) expression is regulated by microRNAs miR-26a and miR-26b allele-specific binding.Semantic proximity Read ↗

Genetic association of the GDNF alpha-receptor genes with schizophrenia and clozapine response.Semantic proximity Read ↗

Polymorphism in the 3'-UTR of LIF but Not in the ATF6B Gene Associates with Schizophrenia Susceptibility: a Case-Control Study and In Silico Analyses.Semantic proximity Read ↗

3' UTR (AGG)n repeat of glial cell line-derived neurotrophic factor (GDNF) gene polymorphism in schizophrenia.Semantic proximity Read ↗

New alterations at potentially regulated regions of the Glial Derived Neurotrophic Factor gene in bipolar disorder.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.