Article

Celecoxib added to risperidone for depressive symptoms in first-episode and drug naïve schizophrenia: Pharmacogenetic impact of BDNF gene polymorphisms

2022-06-01

Abstract excerpt

<title>Abstract</title> <p>Although depressive symptoms are common in patients with schizophrenia (SCZ), depression is not successfully treated in most SCZ patients. SCZ Patients with comorbid depression may have activated inflammatory responses, and celecoxib, a COX2 inhibitor, can dampen inflammation and improve treatment of depression. BDNF may be associated with the treatment response to antidepressants and h...

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Literature Corpus work: 831a69fe-7c63-5657-906c-8e650c2de415
DOI: 10.21203/rs.3.rs-1700453/v1

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