Article
Quantitative live-cell analysis of microtubule-uncoupled cargo-protein sorting in the ER.
Journal of cell science - 15 Mar 2008
Dukhovny Anna, Papadopulos Andreas, Hirschberg Koret
Abstract excerpt
The sorting and concentration of cargo proteins within ER exit sites (ERESs) is a fundamental function of the secretory machinery. The mechanism by which peripheral coat complexes and their small GTPase effectors mediate this function with export membrane domains is only partially understood. The secretory-machinery-mediated sorting to ERESs is a process that counters the entropy-driven even distribution of...
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