Mutation screening of PTPN22: association of the 1858T-allele with Addison's disease.

doi:10.1038/ejhg.2008.33

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

Mutation screening of PTPN22: association of the 1858T-allele with Addison's disease.

European journal of human genetics : EJHG - 1 Aug 2008

Skinningsrud Beate, Husebye Eystein S, Gervin Kristina, Løvås Kristian, Blomhoff Anne, Wolff Anette B, Kemp E Helen, Egeland Thore, Undlien Dag E

Abstract excerpt

The tyrosine-protein phosphatase non-receptor type 22 (PTPN22) gene was recently identified as an important genetic susceptibility factor in several autoimmune diseases. The increased risk has been broadly explained by the 1858T-allele (rs2476601). As two smaller studies on Addison's disease (AD) have shown diverging results, we aimed to elucidate the predisposing effect of the single-nucleotide polymorphism...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Addison Disease

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Aged, 80 and over

Share to Infant

Share to Meta-Analysis as Topic

Share to Mutation, Missense

Share to Norway

Share to Protein Tyrosine Phosphatase, Non-Receptor Type 22

Share to United Kingdom

Source

Open in PubMed

Identifiers

PMID: 18301444
DOI: 10.1038/ejhg.2008.33

Genes

PTPN22

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Mutation screening of PTPN22: association of the 1858T-allele with Addison's disease.PMID 18301444Read ↗

The tryptophan 620 allele of the lymphoid tyrosine phosphatase (PTPN22) gene predisposes to autoimmune Addison's disease.Semantic proximity Read ↗

Sex-specific association of PTPN22 1858T with type 1 diabetes but not with Hashimoto’s thyroiditis or Addison’s disease in the German populationSemantic proximity Read ↗

Protein tyrosine phosphatase non-receptor type 22 gene variants at position 1858 are associated with type 1 and type 2 diabetes in Estonian population.Semantic proximity Read ↗

Differential association of the PTPN22 coding variant with autoimmune diseases in a Dutch population.Semantic proximity Read ↗

Association of PTPN22+1858C/T polymorphism with Type 1 diabetes in the North Indian population.Semantic proximity Read ↗

The PTPN22 C1858T functional polymorphism and autoimmune diseases--a meta-analysis.Semantic proximity Read ↗

The 1858T PTPN22 gene variant contributes to a genetic risk of type 1 diabetes in a Ukrainian population.Semantic proximity Read ↗

PTPN22 R620W functional variant in type 1 diabetes and autoimmunity related traits.Semantic proximity Read ↗

CTLA-4 as a genetic determinant in autoimmune Addison's disease.Semantic proximity Read ↗

Association analysis of the 1858C>T polymorphism in the PTPN22 gene in juvenile idiopathic arthritis and other autoimmune diseases.Semantic proximity Read ↗

Association of Protein Tyrosine Phosphatase Nonreceptor 22 (PTPN22) C1858T gene polymorphism with susceptibility to autoimmune thyroid diseases: a meta-analysis.Semantic proximity Read ↗

PTPN22 C1858T polymorphism in Colombian patients with autoimmune diseases.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.