Article
The 10,400- and 14,500-dalton proteins encoded by region E3 of adenovirus function together to protect many but not all mouse cell lines against lysis by tumor necrosis factor.
Journal of virology - 1 Aug 1991
Gooding L R, Ranheim T S, Tollefson A E, Aquino L, Duerksen-Hughes P, Horton T M, Wold W S
Abstract excerpt
We have reported that the E3 14,700-dalton protein (E3 14.7K protein) protects adenovirus-infected mouse C3HA fibroblasts against lysis by tumor necrosis factor (TNF) (L. R. Gooding, L. W. Elmore, A. E. Tollefson, H. A. Brady, and W. S. M. Wold, Cell 53:341-346, 1988). We have also observed that...
Topics
- Adenoviridae
- Adenovirus Early Proteins
- Animals
- Cell Line
- Cell Survival
- Fibroblasts
- Mice
- Mutation
- Oncogene Proteins, Viral
- Precipitin Tests
- Tumor Cells, Cultured
- Tumor Necrosis Factor-alpha