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Article

Haplotype of the angiotensinogen gene is associated with coronary heart disease in familial hypercholesterolemia.

Journal of hypertension - 1 Mar 2008

van der Net Jeroen B, Isaacs Aaron, Dallinga-Thie Geesje M, Kastelein John Jp, Defesche Joep C, Steyerberg Ewout W, Sijbrands Eric Jg

Abstract excerpt

OBJECTIVE: Familial hypercholesterolemia is characterized by high plasma low-density lipoprotein cholesterol levels and premature coronary heart disease. Despite the monogenetic origin of familial hypercholesterolemia, the incidence of coronary heart disease varies considerably among patients, which is only partly explained by classical risk factors. Hypertension is an important risk factor for coronary heart...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 18300856
DOI: 10.1097/HJH.0b013e3282f2d33c

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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