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Article

T-type current modulation by the actin-binding protein Kelch-like 1.

American journal of physiology. Cell physiology - 1 Jun 2010

Aromolaran K A, Benzow K A, Cribbs L L, Koob M D, Piedras-Rentería E S

Abstract excerpt

We report a novel form of modulation of T-type calcium currents carried out by the neuronal actin-binding protein (ABP) Kelch-like 1 (KLHL1). KLHL1 is a constitutive neuronal ABP localized to the soma and dendritic arbors; its genetic elimination in Purkinje neurons leads to dendritic atrophy and...

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Source

Identifiers

PMID: 20147652
DOI: 10.1152/ajpcell.00235.2009

Genes

KLHL1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20147652-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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