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Article

Decoding the Cardiac Actions of Protein Kinase D Isoforms.

Molecular pharmacology - 1 Dec 2021

Steinberg Susan F

Abstract excerpt

Protein kinase D (PKD) consists of a family of three structurally related enzymes that play key roles in a wide range of biological functions that contribute to the evolution of cardiac hypertrophy and heart failure. PKD1 (the founding member of this enzyme family) has been implicated in the phosphorylation of substrates that regulate cardiac hypertrophy, contraction, and susceptibility to ischemia/reperfusion...

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Share to Heart Defects, Congenital
Share to Isoenzymes
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Myocytes, Cardiac

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Source

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Identifiers

PMID: 34531296
DOI: 10.1124/molpharm.121.000341
PMCID: PMC8626784

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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