Article
Filamin C: a novel component of the KCNE2 interactome during hypoxia.
Cardiovascular journal of Africa - 1 Jan 2000
Neethling Annika, Mouton Jomien, Loos Ben, Corfield Valerie, de Villiers Carin, Kinnear Craig
Abstract excerpt
AIM: KCNE2 encodes for the potassium voltage-gated channel, KCNE2. Mutations in KCNE2 have been associated with long-QT syndrome (LQTS). While KCNE2 has been extensively studied, the functions of its C-terminal domain remain inadequately described. Here, we aimed to elucidate the functions of this domain by identifying its protein interactors using yeast two-hybrid analysis. METHODS: The C-terminal domain of...
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