Article
Characterization of the immunogenetic basis of ultraviolet-B light effects on contact hypersensitivity induction.
Immunology - 1 Mar 1994
Kurimoto I, Streilein J W
Abstract excerpt
Ultraviolet-B (UVB) light has proven to be deleterious to the skin immune system in mice, and one major consequence is impairment of the induction of contact hypersensitivity (CH) to haptens applied to UVB-exposed skin. It has been shown recently that the damaging effects of UVB on CH are mediated primarily by tumour necrosis factor-alpha (TNF-alpha). Moreover, not all strains of mice are equally susceptible to...
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