HIV genes diversify in B cells.

Abstract excerpt

Mutation of the human immunodeficiency virus by host cells inhibits viral dissemination by creating non-functional variants. However, viral mutation does not always eliminate the ability of the virus to disseminate and, in fact, is thought to promote persistence by generating functional mutants that evade immunity or drugs. How and where HIV mutates is not known. Accordingly, where and to what extent variants...

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• Share to B-Lymphocytes
• Share to Complementarity Determining Regions
• Share to Drug Resistance, Multiple, Viral