Article
The mutable vaccine for mutable viruses.
Immunotherapy - 1 Jun 2017
Cascalho Marilia, Balin Samuel J, Platt Jeffrey L
Abstract excerpt
Mutable viruses, such as HIV, pose difficult obstacles to prevention and/or control by vaccination. Mutable viruses rapidly diversify in populations and in individuals, impeding development of effective vaccines. We devised the 'mutable vaccine' to appropriate the properties of mutable viruses that undermine conventional strategies. The vaccine consists of a DNA construct encoding viral antigen and regulatory...
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