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Article

TLR and MBL gene polymorphisms in severe acute pancreatitis.

Molecular diagnosis & therapy - 1 Jan 2008

Zhang DianLiang, Zheng HongMei, Zhou YanBing, Yu BaoJun, Li JieShou

Abstract excerpt

BACKGROUND AND OBJECTIVE: Mannose-binding lectin (MBL) and toll-like receptor (TLR)-4 gene polymorphisms have been implicated in inflammatory episodes in a number of studies. In view of the inflammatory nature of acute pancreatitis, we aimed to determine the predictive value of two point mutations in the promoter region at position -550 (H/L variants) and -221 (X/Y variants) of the MBL2 gene, and the Asp299Gly...

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Topics

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Share to Acute Disease
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Share to Genetic Predisposition to Disease

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Mannose-Binding Lectin

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Share to Polymerase Chain Reaction

Share to Polymorphism, Genetic

Share to Toll-Like Receptor 4

Source

Identifiers

PMID: 18288881
DOI: 10.1007/BF03256267

Genes

MBL2
TLR4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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