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Article

The role of Toll-like receptor polymorphisms in acute pancreatitis occurrence and severity.

Pancreas - 1 Apr 2015

Matas-Cobos Ana M, Redondo-Cerezo Eduardo, Alegría-Motte Carlos, Martínez-Chamorro Alba, Saenz-López Pablo, Jiménez Pilar, Jiménez Miguel Ruíz-Cabello, González-Calvín Jorge Luis, de Teresa Javier, Osuna Francisco Ruiz-Cabello

Abstract excerpt

OBJECTIVES: Toll-like receptors (TLRs) are damage-associated molecular patterns receptors, which are essential in the activation of the inflammasome cascade, required for the initiation of inflammation. We hypothesized that changes in the function of these receptors caused by genetic polymorphisms in their encoding genes could determine acute pancreatitis (AP) incidence or severity. METHODS: Two hundred...

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Source

Identifiers

PMID: 25423559
DOI: 10.1097/MPA.0000000000000272

Genes

TLR3
TLR6
TLR4
TLR5
TLR1
TLR10
TLR2
TLR7
TLR9

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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