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Article

Microsatellite polymorphism in intron 2 of human Toll-like receptor 2 gene is associated with susceptibility to acute pancreatitis in Japan.

Human immunology - 1 Mar 2009

Takagi Yasuhiko, Masamune Atsushi, Kume Kiyoshi, Satoh Akihiko, Kikuta Kazuhiro, Watanabe Takashi, Satoh Kennichi, Hirota Morihisa, Shimosegawa Tooru

Abstract excerpt

This study evaluated the association of the polymorphisms in the Toll-like receptor (TLR)2 and TLR4 genes with acute pancreatitis (AP) in Japan. The numbers of guanine-thymine [(GT)n] repeats in intron 2 of the TLR2 gene were counted in 202 unrelated patients with AP (80 with severe and 122 with mild disease) and in 286 healthy controls, using polymerase chain reaction and Genescan analysis. The alleles were...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 19280717
DOI: 10.1016/j.humimm.2009.01.006

Genes

TLR2
TLR4

Provenance

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