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The modification landscape of Pseudomonas aeruginosa tRNAs

29 Apr 2024

Abstract excerpt

RNA modifications have a substantial impact on tRNA function, with modifications in the anticodon loop contributing to translational fidelity and modifications in the tRNA core impacting structural stability. In bacteria, tRNA modifications are crucial for responding to stress and regulating the expression of virulence factors. Although tRNA modifications are well-characterized in a few model organisms, our...

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PMID: 38684317
DOI: 10.1261/rna.080004.124

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