The modification landscape of <i>P. aeruginosa</i> tRNAs

Abstract excerpt

RNA modifications have a substantial impact on tRNA function, with modifications in the anticodon loop contributing to translational fidelity and modifications in the tRNA core impacting structural stability. In bacteria, tRNA modifications are crucial for responding to stress and regulating the expression of virulence factors. Although tRNA modifications are well-characterized in a few model organisms, our knowle...

Topics

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• Infective Endocarditis Diagnosis and Management
• Nucleic Acid Conformation
• Protein Biosynthesis
• RNA and protein synthesis mechanisms
• RNA, Bacterial
• RNA-Binding Proteins
• RNA modifications and cancer
• RNA Processing, Post-Transcriptional

Identifiers and source

Literature Corpus work

072214e3-52aa-53d2-8b74-f75f68f518f9

DOI

10.1101/2024.02.21.581370