Article
Association of CYP1A1 Msp1 polymorphism with tobacco-related risk of gallbladder cancer in a north Indian population.
European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP) - 1 Apr 2008
Pandey Sachchida Nand, Choudhuri Gourdas, Mittal Balraj
Abstract excerpt
Polymorphisms in the gene encoding the metabolic enzyme cytochrome P450 1A1 (CYP1A1) might contribute to the variability in individual susceptibility to gallbladder cancer (GBC). This study comprised 142 consecutive cases of proven GBC and 171 healthy participants of similar ethnicity. CYP1A1 6235 T/C transition was analyzed using polymerase chain reaction-restriction fragment length polymorphism. The CC genotype...
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