Article
Effect of genetic predisposition on the risk of gallbladder cancer in Hungary.
Asian Pacific journal of cancer prevention : APJCP - 1 Jan 2000
Kimura Akira, Tsuchiya Yasuo, Lang Istvan, Zoltan Szentirmay, Nakadaira Hiroto, Ajioka Yoichi, Kiyohara Chikako, Oyama Mari, Nakamura Kazutoshi
Abstract excerpt
A CYP1A1 polymorphism has been associated with an increased risk for gallbladder cancer (GBC) in Japanese women. However, genetic risk factors for GBC in Hungary, where the population has a relatively high GBC incidence, has not been well studied. We therefore tested associations between CYP1A1 T3801C, CYP1A1 Ile462Val, GSTM1deletion, and TP53 Arg72Pro and GBC in Hungary. Genomic DNA was extracted from peripheral...
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