Article
Superovulation alters the expression of imprinted genes in the midgestation mouse placenta.
Human molecular genetics - 1 Jun 2008
Fortier Amanda L, Lopes Flavia L, Darricarrère Nicole, Martel Josée, Trasler Jacquetta M
Abstract excerpt
Imprinted genes play important roles in embryonic growth and development as well as in placental function. Many imprinted genes acquire their epigenetic marks during oocyte growth, and this period may be susceptible to epigenetic disruption following hormonal stimulation. Superovulation has been shown to affect growth and development of the embryo, but an effect on imprinted genes has not been shown in...
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