Article
Superovulation induces alterations in the epigenome of zygotes, and results in differences in gene expression at the blastocyst stage in mice
1 Mar 2015
Abstract excerpt
Gamete and embryo manipulations can result in alterations to the epigenome, and are associated with altered gene expression. The initial objective of this study was to determine the transcript level of several epigenetic modifiers in embryos that had been cultured from the 2-cell stage until the late-blastocyst stage in four culture conditions. Cultured embryos were compared to control, in vivo-produced late...
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