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Article

Manipulations of mouse embryos prior to implantation result in aberrant expression of imprinted genes on day 9.5 of development.

Human molecular genetics - 1 Jan 2008

Rivera Rocío M, Stein Paula, Weaver Jamie R, Mager Jesse, Schultz Richard M, Bartolomei Marisa S

Abstract excerpt

In vitro culture of mouse embryos results in loss of imprinting. The aim of the present study was to examine how two of the techniques commonly used during assisted reproduction, namely embryo culture and embryo transfer, affect genomic imprinting after implantation in the mouse. F1 hybrid mouse embryos were subjected to three experimental conditions: control (unmanipulated), embryo transfer and in-vitro-culture...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 17901045
DOI: 10.1093/hmg/ddm280

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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