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Article

Dual effects of superovulation: loss of maternal and paternal imprinted methylation in a dose-dependent manner

4 Oct 2009

Abstract excerpt

Superovulation or ovarian stimulation is currently an indispensable assisted reproductive technology (ART) for human subfertility/infertility treatment. Recently, increased frequencies of imprinting disorders have been correlated with ARTs. Significantly, for Angelman and Beckwith-Wiedemann Syndromes, patients have been identified where ovarian stimulation was the only procedure used by the couple undergoing ART....

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Share to Epigenetics and DNA Methylation
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PMID: 19805400
DOI: 10.1093/hmg/ddp465

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