Article
HSP90-buffered genetic variation is common in Arabidopsis thaliana.
Proceedings of the National Academy of Sciences of the United States of America - 26 Feb 2008
Sangster Todd A, Salathia Neeraj, Lee Hana N, Watanabe Etsuko, Schellenberg Kurt, Morneau Keith, Wang Hui, Undurraga Soledad, Queitsch Christine, Lindquist Susan
Abstract excerpt
HSP90 is a protein chaperone particularly important in the maturation of a diverse set of proteins that regulate key steps in a multitude of biological processes. Alterations in HSP90 function produce altered phenotypes at low penetrance in natural populations. Previous work has shown that at least some of these phenotypes are due to genetic variation that remains phenotypically cryptic until it is revealed by...
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