Article
Candida albicans-specific Ly-2+ lymphocytes with cytolytic activity.
European journal of immunology - 1 Jun 1991
Romani L, Mocci S, Cenci E, Rossi R, Puccetti P, Bistoni F
Abstract excerpt
To determine whether antigen (Ag)-specific cytotoxic T lymphocytes are generated during experimental Candida albicans infection, purified L3T4+ and Ly-2+ lymphocytes from immunized mice were cultured in the presence of syngeneic accessory cells, C. albicans Ag, and interleukin 2. Yeast-infected bone marrow macrophages were used as target cells in a standard 51Cr-release assay. Freshly isolated L3T4+ and Ly-2+...
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