Article
Cytotoxic events taking place in the lung of patients with HIV-1 infection. Evidence of an intrinsic defect of the major histocompatibility complex-unrestricted killing partially restored by the incubation with rIL-2.
The American review of respiratory disease - 1 Sept 1990
Agostini C, Zambello R, Trentin L, Feruglio C, Masciarelli M, Siviero F, Poletti V, Spiga L, Gritti F, Semenzato G
Abstract excerpt
To characterize the cytotoxic events taking place in the lung of patients with HIV-1 infection, we studied the cells recovered from the bronchoalveolar lavage (BAL) of nine patients with AIDS, seven patients with AIDS-related complex, and two patients with lymphadenopathy. Phenotypic analysis was coupled to a series of functional evaluations of nonspecific cytotoxic abilities performed on lung effectors,...
Topics
- Acquired Immunodeficiency Syndrome
- Adult
- Antigens, CD
- Bronchoalveolar Lavage Fluid
- Cytotoxicity, Immunologic
- Female
- Humans
- Interleukin-2
- Killer Cells, Natural