Article
Motility screen identifies Drosophila IGF-II mRNA-binding protein--zipcode-binding protein acting in oogenesis and synaptogenesis.
PLoS genetics - 1 Feb 2008
Boylan Kristin L M, Mische Sarah, Li Mingang, Marqués Guillermo, Morin Xavier, Chia William, Hays Thomas S
Abstract excerpt
The localization of specific mRNAs can establish local protein gradients that generate and control the development of cellular asymmetries. While all evidence underscores the importance of the cytoskeleton in the transport and localization of RNAs, we have limited knowledge of how these events are regulated. Using a visual screen for motile proteins in a collection of GFP protein trap lines, we identified the...
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