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Article

Expression profiles reveal parallel evolution of epistatic interactions involving the CRP regulon in Escherichia coli.

PLoS genetics - 1 Feb 2008

Cooper Tim F, Remold Susanna K, Lenski Richard E, Schneider Dominique

Abstract excerpt

The extent and nature of epistatic interactions between mutations are issues of fundamental importance in evolutionary biology. However, they are difficult to study and their influence on adaptation remains poorly understood. Here, we use a systems-level approach to examine epistatic interactions...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 18282111
DOI: 10.1371/journal.pgen.0040035
PMCID: PMC2242816

Genes

CRP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18282111-2026-09-02.1. Manifest publication-graph-cohort-2026-09-02.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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