Parallel adaptive evolution cultures of Escherichia coli lead to convergent growth phenotypes with different gene expression states.

doi:10.1101/gr.3832305

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Article

Parallel adaptive evolution cultures of Escherichia coli lead to convergent growth phenotypes with different gene expression states.

Genome research - 1 Oct 2005

Fong Stephen S, Joyce Andrew R, Palsson Bernhard Ø

Abstract excerpt

Laboratory evolution can be used to address fundamental questions about adaptation to selection pressures and, ultimately, the process of evolution. In this study, we investigated the reproducibility of growth phenotypes and global gene expression states during adaptive evolution. The results from parallel, replicate adaptive evolution experiments of Escherichia coli K-12 MG1655 grown on either lactate or...

Topics

Biological Evolution
Escherichia coli
Gene Expression Profiling
Phenotype
RNA, Messenger
Transcription, Genetic

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Identifiers

PMID: 16204189
DOI: 10.1101/gr.3832305
PMCID: PMC1240078

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