Article
Parallel changes in global protein profiles during long-term experimental evolution in Escherichia coli.
Genetics - 1 Aug 2006
Pelosi Ludovic, Kühn Lauriane, Guetta Dorian, Garin Jérôme, Geiselmann Johannes, Lenski Richard E, Schneider Dominique
Abstract excerpt
Twelve populations of Escherichia coli evolved in and adapted to a glucose-limited environment from a common ancestor. We used two-dimensional protein electrophoresis to compare two evolved clones, isolated from independently derived populations after 20,000 generations. Exceptional parallelism was detected. We compared the observed changes in protein expression profiles with previously characterized global...
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