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Article

Polymorphic markers of the fibrillin-1 gene and systemic sclerosis in European Caucasian patients.

The Journal of rheumatology - 1 Apr 2008

Wipff Julien, Giraud Matthieu, Sibilia Jean, Mouthon Luc, Meyer Olivier, Tiev Kiet, Airo Paolo, Caramaschi Paola, Guiducci Serena, Garchon Henri Jean, Matucci-Cerinic Marco, Kahan André, Avouac Jéröme, Boileau Catherine, Allanore Yannick

Abstract excerpt

OBJECTIVE: Evidence suggests that systemic sclerosis (SSc) belongs to the fibrillinopathic disorders. Significant associations have been found with the fibrillin-1 gene (FBN1) in Choctaw and Japanese populations. We investigated FBN1 polymorphisms in cohorts of European Caucasian patients. METHODS: We investigated 6 FBN1 polymorphisms in 2 cohorts: one with 399 French subjects (243 SSc patients/156 matched...

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PMID: 18278837

Genes

FBN1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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