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Article

Association of GTF2I, NFKB1, and TYK2 Regional Polymorphisms With Systemic Sclerosis in a Chinese Han Population.

Frontiers in immunology - 1 Jan 2021

Liu Chenxi, Yan Songxin, Chen Haizhen, Wu Ziyan, Li Liubing, Cheng Linlin, Li Haolong, Li Yongzhe

Abstract excerpt

Objectives: Systemic sclerosis (SSc) is an uncommon autoimmune disease that varies with ethnicity. Single nucleotide polymorphisms (SNPs) in the GTFSI, NFKB1, and TYK2 genes have been reported to be associated with SSc in other populations and in individuals with various autoimmune diseases. This study aimed to investigate the association between these SNPs and susceptibility to SSc in a Chinese Han population....

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Source

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Identifiers

PMID: 34248934
DOI: 10.3389/fimmu.2021.640083
PMCID: PMC8261294

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