Article
Association of microsatellite markers near the fibrillin 1 gene on human chromosome 15q with scleroderma in a Native American population.
Arthritis and rheumatism - 1 Oct 1998
Tan F K, Stivers D N, Foster M W, Chakraborty R, Howard R F, Milewicz D M, Arnett F C
Abstract excerpt
OBJECTIVE: To localize disease genes for scleroderma, or systemic sclerosis (SSc), in a population of Choctaw Native Americans with a high prevalence of SSc, in which there is evidence of a possible founder effect. METHODS: A candidate gene approach was used in which microsatellite alleles on hum...
Topics
- Alleles
- Chromosomes, Human, Pair 15
- Fibrillin-1
- Fibrillins
- Genotype
- Haplotypes
- Humans
- Indians, North American
- Microfilament Proteins
- Microsatellite Repeats
- Oklahoma
- Pedigree
- Phenotype
- Prevalence
- Scleroderma, Systemic