Article
Association of SLC22A4/5 polymorphisms with steroid responsiveness of inflammatory bowel disease in Japan.
Diseases of the colon and rectum - 1 May 2008
Nakahara Seiya, Arimura Yoshiaki, Saito Katsuhiko, Goto Akira, Motoya Satoshi, Shinomura Yasuhisa, Miyamoto Atsushi, Imai Kohzoh
Abstract excerpt
PURPOSE: We investigated the association between steroid responsiveness and single nucleotide polymorphisms of SLC22A4/A5 located within inflammatory bowel disease 5 locus. Our goal is personalized steroid therapy adjusted to match individual variations in drug responsiveness in each inflammatory bowel disease patient. METHODS: Unrelated Japanese cohorts of 94 patients with Crohn's, 94 patients with ulcerative...
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