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Article

Topotecan distribution in an anephric infant with therapy-resistant bilateral Wilms tumor with a novel germline WT1 gene mutation.

Cancer chemotherapy and pharmacology - 1 Nov 2008

Lugtenberg Rieneke T, Cransberg Karlien, Loos Walter J, Wagner Anja, Alders Marielle, van den Heuvel-Eibrink Marry M

Abstract excerpt

The therapeutic strategy for bilateral Wilms tumor (WT) remains a challenge. Especially in cases with chemotherapy resistant disease, bilateral nephrectomy is sometimes inevitable. For optimal cure rates stage V WT patients benefit from adjuvant treatment; however, there are limited data availabl...

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Identifiers

PMID: 18273617
DOI: 10.1007/s00280-008-0694-x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18273617-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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