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Article

Common variants near IKZF1 are associated with primary Sjögren's syndrome in Han Chinese.

PloS one - 1 Jan 2017

Qu Susu, Du Yang, Chang Suhua, Guo Liyuan, Fang Kechi, Li Yongzhe, Zhang Fengchun, Zhang Kunlin, Wang Jing

Abstract excerpt

Primary Sjögren's syndrome (pSS) is a systematic autoimmune disease with evidence of genetic predisposition. The IKZF1 (IKAROS family zinc finger 1 (Ikaros)) gene is located at 7p12.2, encodes a transcription factor related to chromatin remodeling, regulates lymphocyte differentiation, and has been reported to be associated with some autoimmune diseases. However, there have been no reports of an association...

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Source

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Identifiers

PMID: 28552951
DOI: 10.1371/journal.pone.0177320
PMCID: PMC5446195

Genes

IKZF1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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