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Article

[Isolation and expansion of glioma-infiltrating lymphocytes in vitro: an analysis of their surface phenotypes and antitumor activities].

[Hokkaido igaku zasshi] The Hokkaido journal of medical science - 1 Nov 1991

Sawamura Y

Abstract excerpt

The present study was conducted in order to examine the feasibility of isolating and growing glioma-infiltrating lymphocytes in vitro as possible effector cells for use in an adoptive immunotherapy. Thirty surgical specimens obtained from patients with malignant astrocytomas were studied. The glioma-infiltrating lymphocytes were separated from tumor tissue, expanded in the presence of interleukin-2, and evaluated...

Topics

Adult
Aged
Antigens, CD
Cytotoxicity, Immunologic
Female
Glioma
Humans
Immunotherapy, Adoptive
Interleukin-2
Killer Cells, Lymphokine-Activated
Lymphocyte Activation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Lymphocytes, Tumor-Infiltrating

Male

Middle Aged

Phenotype

Tumor Cells, Cultured

Source

Identifiers

PMID: 1783372

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1783372-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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