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Article

The critical role of substrate-protein hydrogen bonding in the control of regioselective hydroxylation in p450cin.

The Journal of biological chemistry - 18 Apr 2008

Meharenna Yergalem T, Slessor Kate E, Cavaignac Sonia M, Poulos Thomas L, De Voss James J

Abstract excerpt

Cytochrome P450cin (CYP176A1) is a bacterial P450 isolated from Citrobacter braakii that catalyzes the hydroxylation of cineole to (S)-6beta-hydroxycineole. This initiates the biodegradation of cineole, enabling C. braakii to live on cineole as its sole source of carbon and energy. P450cin lacks...

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Identifiers

PMID: 18270198
DOI: 10.1074/jbc.M709722200
PMCID: PMC2447660

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18270198-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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