Article
Extraction of DNA from serum for high-throughput genotyping: findings from pilot studies within the Prostate Cancer Prevention Trial.
Urology - 1 May 2008
Hoque Ashraful, Goodman Phyllis, Ambrosone Christine B, Figg William D, Price Douglas K, Kopp William, Wu Xifeng, Conroy Jeffrey, Lehman Teresa A, Santella Regina M
Abstract excerpt
OBJECTIVES: Deoxyribonucleic acid (DNA) extraction from blood and genotyping for candidate single nucleotide polymorphisms (SNP) is now an important part of almost all molecular epidemiologic studies. However, in many studies the amount of blood sample is limited or only serum is available. We conducted several pilot studies to identify methods for DNA extraction and high-throughput SNP genotyping of both white...
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