Article
Sulphadoxine/pyrimethamine versus amodiaquine for treating uncomplicated childhood malaria in Gabon: a randomized trial to guide national policy.
Malaria journal - 12 Feb 2008
Nsimba Basile, Guiyedi Vincent, Mabika-Mamfoumbi Modeste, Mourou-Mbina Jean Romain, Ngoungou Edgard, Bouyou-Akotet Marielle, Loembet Romaric, Durand Rémy, Le Bras Jacques, Kombila Maryvonne
Abstract excerpt
BACKGROUND: In Gabon, following the adoption of amodiaquine/artesunate combination (AQ/AS) as first-line treatment of malaria and of sulphadoxine/pyrimethamine (SP) for preventive intermittent treatment of pregnant women, a clinical trial of SP versus AQ was conducted in a sub-urban area. This is the first study carried out in Gabon following the WHO guidelines. METHODS: A random comparison of the efficacy of AQ...
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