Article
High prevalence of genotypes associated with sulfadoxine/pyrimethamine resistance in the rural area of Fougamou, Gabon.
Journal of global antimicrobial resistance - 1 Jun 2021
Boukoumba Fleuramie Mirembou, Lekana-Douki Jean Bernard, Matsiegui Pierre Blaise, Moukodoum Damiella Nancy, Adegnika Ayola Akim, Oyegue-Liabagui Sandrine Lydie
Abstract excerpt
OBJECTIVES: Pregnancy-associated malaria (PAM) is a complex form of malaria. To prevent PAM, several African countries have adopted intermittent preventive treatment with sulfadoxine/pyrimethamine (IPT-SP). However, resistance to SP has been reported, associated with mutations in the genes Plasmodium falciparum dihydropteroate synthase (Pfdhps) and P. falciparum dihydrofolate reductase (Pfdhfr). The aim of this...
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