Article
Efficacy of artesunate + sulphadoxine/pyrimethamine and artemether + lumefantrine and dhfr and dhps mutations in Somalia: evidence for updating the malaria treatment policy.
Tropical medicine & international health : TM & IH - 1 Apr 2017
Warsame Marian, Hassan Abdikarim Hussein, Hassan Abdillahi Mohamed, Arale Abdulkadir Mohamed, Jibril Ali Mohamed, Mohamud Said Abdulkadir, Barrette Amy, Muse Abdikarim Yusuf, Yusuf Fahmi Essa, Nada Rania A, Amran Jamal Ghilan Hefzullah
Abstract excerpt
OBJECTIVE: To determine the therapeutic efficacy of artesunate + sulphadoxine/pyrimethamine (AS + SP) and artemether + lumefantrine (AL), and to investigate the presence of molecular mutations associated with resistance, to inform national malaria treatment policy. METHODS: One-arm prospective studies were conducted in three study sites in Somalia in 2013 and 2015 to evaluate the efficacy of AS + SP and AL among...
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