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Article

Supervised Lowess normalization of comparative genome hybridization data--application to lactococcal strain comparisons.

BMC bioinformatics - 11 Feb 2008

van Hijum Sacha A F T, Baerends Richard J S, Zomer Aldert L, Karsens Harma A, Martin-Requena Victoria, Trelles Oswaldo, Kok Jan, Kuipers Oscar P

Abstract excerpt

BACKGROUND: Array-based comparative genome hybridization (aCGH) is commonly used to determine the genomic content of bacterial strains. Since prokaryotes in general have less conserved genome sequences than eukaryotes, sequence divergences between the genes in the genomes used for an aCGH experim...

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Identifiers

PMID: 18267014
DOI: 10.1186/1471-2105-9-93
PMCID: PMC2275246

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-18267014-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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