Article
Improved analytical methods for microarray-based genome-composition analysis.
Genome biology - 29 Oct 2002
Kim Charles C, Joyce Elizabeth A, Chan Kaman, Falkow Stanley
Abstract excerpt
BACKGROUND: Whereas genome sequencing has given us high-resolution pictures of many different species of bacteria, microarrays provide a means of obtaining information on genome composition for many strains of a given species. Genome-composition analysis using microarrays, or 'genomotyping', can be used to categorize genes into 'present' and 'divergent' categories based on the level of hybridization signal. This...
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