Article
Optimal control and analysis of two-color genomotyping experiments using bacterial multistrain arrays.
BMC genomics - 19 May 2008
Pinto Francisco R, Aguiar Sandra I, Melo-Cristino J, Ramirez Mário
Abstract excerpt
BACKGROUND: Microarray comparative genomic hybridization (aCGH) evaluates the distribution of genes of sequenced bacterial strains among unsequenced strains of the same or related species. As genomic sequences from multiple strains of the same species become available, multistrain microarrays are designed, containing spots for every unique gene in all sequenced strains. To perform two-color aCGH experiments with...
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