Article

Amalgams: data-driven amalgamation for the reference-free dimensionality reduction of zero-laden compositional data

2020-02-28

Abstract excerpt

In the health sciences, many data sets produced by next-generation sequencing (NGS) only contain relative information because of biological and technical factors that limit the total number of nucleotides observed for a given sample. As mutually dependent elements, it is not possible to interpret any component in isolation, at least without normalization. The field of compositional data analysis (CoDA) has emerged...

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Literature Corpus work: 905625e2-57a0-5b73-9965-a834b542ca33
DOI: 10.1101/2020.02.27.968677

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