Article
Microarray comparative genomic hybridisation analysis incorporating genomic organisation, and application to enterobacterial plant pathogens.
PLoS computational biology - 1 Aug 2009
Pritchard Leighton, Liu Hui, Booth Clare, Douglas Emma, François Patrice, Schrenzel Jacques, Hedley Peter E, Birch Paul R J, Toth Ian K
Abstract excerpt
Microarray comparative genomic hybridisation (aCGH) provides an estimate of the relative abundance of genomic DNA (gDNA) taken from comparator and reference organisms by hybridisation to a microarray containing probes that represent sequences from the reference organism. The experimental method is used in a number of biological applications, including the detection of human chromosomal aberrations, and in...
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