Article
Human somatic cell gene targeting.
Current protocols in molecular biology - 1 May 2003
Waldman Todd, Lee Carolyn, Nishanian Tagvor G, Kim Jung-Sik
Abstract excerpt
Human somatic cell gene targeting provides a powerful tool to scientists studying gene function in cultured human cells. This technology allows scientists to knock out genes in human somatic cells in a fashion analogous to the creation of knockout mice. Human somatic cell gene targeting brings the power of genetics to the study of human genes in human cells by making it possible to compare cells or individuals...
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