Article
Reward sensitivity and the D2 dopamine receptor gene: A case-control study of binge eating disorder.
Progress in neuro-psychopharmacology & biological psychiatry - 1 Apr 2008
Davis Caroline, Levitan Robert D, Kaplan Allan S, Carter Jacqueline, Reid Caroline, Curtis Claire, Patte Karen, Hwang Rudi, Kennedy James L
Abstract excerpt
OBJECTIVE: The sensitivity of dopamine reward pathways has been implicated in the risk for various psychiatric disorders including compulsive overeating. The evidence is divided, however, about the direction of causal association. One argument is that a Reward Deficiency Syndrome is the risk factor, while others contend that hyper-sensitivity to reward enhances the motivation for pleasurable activities like...
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