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Article

Epistatic interactions implicating dopaminergic genes in bulimia nervosa (BN): relationships to eating- and personality-related psychopathology.

Progress in neuro-psychopharmacology & biological psychiatry - 1 Oct 2012

Thaler Lea, Groleau Patricia, Badawi Guilaine, Sycz Lindsay, Zeramdini Nadia, Too Andrea, Israel Mimi, Joober Ridha, Bruce Kenneth R, Steiger Howard

Abstract excerpt

We explored the influence of interactions between polymorphisms acting upon postsynaptic receptors (DRD2 TaqA1 rs1800497 and DRD4 7R) and dopamine regulators (COMT rs4680 and DAT1) on the expression of eating symptoms and personality traits in women with bulimia-spectrum eating disorders. We had 269 bulimic women provide blood for genetic assays, and measured eating-disorder symptoms and psychopathological traits...

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Source

Identifiers

PMID: 22683321
DOI: 10.1016/j.pnpbp.2012.05.019

Genes

COMT
DRD2
DRD4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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